Nature (Nature) | Latest Research

Access through your institution Buy or subscribe arising from: Y. Xing et al. Nature https://doi.org/10.1038/s41586-024-07519-5 (2024). The kagome superconductors AV3Sb5 (where A = K, Cs, Rb) exhibit intertwined density waves, uncon

Reply to: Limitations of probing field-induced response with STM

Access through your institution Buy or subscribe replying to: C. Candelora & I. Zeljkovic Nature https://doi.org/10.1038/s41586-026-10126-1 (2026). In our paper1, we demonstrate that the relative intensities of charge-density-wave (

Peripheral immune-inducer dendritic cells drive early-life allergic inflammation

Abstract Atopic diseases associated with allergens, as well as allergic diseases, frequently arise early in life; however, the age-dependent mechanisms governing immune responses to allergens remain poorly understood1. Here we find that in early life, exposure to common allergens triggers a distinc

Argentine fossil rewrites evolutionary history of a baffling dinosaur clade

Abstract Alvarezsauroids are an enigmatic clade of predominantly small-bodied theropod dinosaurs that are known mainly from the Jurassic to Cretaceous periods of Asia and South America1,2,3. Late Cretaceous alvarezsauroids possess specialized forelimbs adapted for digging4,5, minute supernumerary t

Echinoderm stereom gradient structures enable mechanoelectrical perception

Abstract Cellular solids ubiquitously exist in natural systems and are crucial for living organisms1,2. Their unique smooth branch and node morphologies are often seen as adaptations for enhanced mechanical performance3,4. Exploring alternative evolutionary functions can enrich the understanding of

Compact deep neural network models of the visual cortex

Abstract A powerful approach to understand the computations carried out by the visual cortex is to build models that predict neural responses to any arbitrary image. Deep neural networks (DNNs) have emerged as the leading predictive models1,2, yet their underlying computations remain buried beneath

Pivoting colloidal assemblies exhibit mechanical metamaterial behaviour

Abstract Biological machines use targeted deformations that can be actuated by Brownian fluctuations. However, although synthetic micromachines can similarly make use of targeted deformations, they are too stiff to be driven by thermal fluctuations and require strong forcing1,2,3. Furthermore, syst

Field-free full switching of chiral antiferromagnetic order

Abstract Chiral antiferromagnets1,2 host octupole order3,4 and combine the advantages of antiferromagnets and ferromagnets. Despite the development of numerous switching strategies5,6,7,8,9, the field-free full switching remains unknown, posing an important obstacle to their practical application i

Cavity-altered superconductivity

Abstract Is it feasible to alter the ground-state properties of a material by engineering its electromagnetic environment? Inspired by theoretical predictions1,2,3,4,5,6,7,8,9,10,11,12, experimental realizations of such cavity-controlled properties without optical excitation are beginning to emerge

OR7A10 GPCR engineering boosts CAR-NK therapy against solid tumours

Abstract Chimeric antigen receptor (CAR)-natural killer (NK) cell therapies hold promise for solid tumours but remain limited because of poor tumour infiltration, persistence and resistance in the tumour microenvironment1,2,3,4. Here, to identify gain-of-function targets that enhance CAR-NK cell ef

Coral microbiomes as reservoirs of unknown genomic and biosynthetic diversity

Abstract Coral reefs are marine biodiversity hotspots that provide a wide range of ecosystem services1. They are reservoirs of bioactive metabolites, many produced by microorganisms associated with reef invertebrate hosts2. However, for the keystone species of coral reefs—the reef-building corals—w

Squeaking at soft–rigid frictional interfaces

Abstract Squeaking is a constant companion in various aspects of our daily lives, whether we slide rubber-soled shoes across hardwood floors1, scrape chalk on a blackboard2, engage the brakes on a bicycle3 or walk with a hip replacement4,5. When two rigid bodies slide over each other, squeaking is

Hydrofluorocarbon electrolytes for energy-dense and low-temperature batteries

Abstract Electrolyte solvents for electrochemical devices have been dominated by oxygen (O)-based and nitrogen (N)-based ligands over the past decades1,2,3,4,5, for which the dipole–ion (Li+, Na+ and so on) interaction usually lays the foundations of ion dissociation and transport but frustrates th

Vectorized instructive signals in cortical dendrites

Abstract Vectorization of teaching signals is a key element of almost all modern machine learning algorithms, including backpropagation, target propagation and reinforcement learning. Vectorization allows a scalable and computationally efficient solution to the credit assignment problem by tailorin

A disease model resource reveals core principles of tissue-specific cancer evolution

Abstract Oncogenes such as KRAS display marked tissue specificity in their oncogenic potential, genetic interactions and phenotypic effects, but the underlying determinants remain largely unresolved1,2,3,4,5. Here, to address these questions, we developed the Mouse Cancer Cell line Atlas, a broad-u

Rewiring an E3 ligase enhances cold resilience and phosphate use in maize

Abstract Cold stress restricts plant growth and inorganic phosphate (Pi) uptake, reducing yield and increasing fertilizer demand1,2,3. Enhancing both cold tolerance and phosphorus use efficiency (PUE) is crucial for sustainable crop productivity. Here we identify the SPX-domain-containing E3 ubiqui

Clonal-aggregative multicellularity tuned by salinity in a choanoflagellate

Abstract Multicellularity evolved independently multiple times in eukaryotes1,2,3,4. Two distinct mechanisms underpin multicellularity5: clonality (serial cell division without sister-cell separation) and aggregation (whereby independent cells assemble into a multicellular entity). Clonal and aggre

Convergent MurJ flippase inhibition by phage lysis proteins

Abstract Antimicrobial drug resistance poses a global health challenge that necessitates the identification of new druggable targets1,2,3. The essential lipid II flippase MurJ is a promising yet underexplored antimicrobial target in bacterial cell wall biosynthesis4,5,6,7. The only known inhibitors

Pancreatic-targeted lipid nanoparticles based on organ capsule filtration

Abstract Achieving pancreatic-targeted delivery marks a breakthrough in treating pancreatic diseases, yet precise delivery remains challenging1. Here we identify an explicit and universal principle for pancreatic-selective delivery and propose a pancreatic-targeted lipid nanoparticle (AH-LNP) for m

A membrane-bound nuclease directly cleaves phage DNA during genome injection

Abstract From mammals to bacteria, the direct recognition and cleavage of viral nucleic acids is a potent defence strategy against viral infection, but it requires mechanisms for distinguishing self from non-self1,2. In bacteria, CRISPR–Cas and restriction-modification systems achieve this discrimi

Ontogeny and transcriptional regulation of Thetis cells

Abstract Thetis cells (TCs) are a recently identified lineage of RORγt+ antigen-presenting cells comprising four subsets including a tolerogenic subset, TC IV, that instructs tolerance to gut microbiota and food antigens1–6. A developmental wave of TCs during early life creates a critical window of

Long-lived remote ion-ion entanglement for scalable quantum repeaters

Abstract Quantum networks, integrating quantum communication, quantum metrology, and distributed quantum computing, could provide secure and efficient information transfer, high-resolution sensing, and an exponential speed-up in information processing1. Deterministic entanglement distribution over

A broadly protective antibody targeting gammaherpesvirus gB

Abstract Gammaherpesvirus is a subfamily of herpesvirus, distinct phylogenetically from alpha- and betaherpesvirus and featured by its oncogenic subtypes, including Epstein-Barr virus and Kaposi’s sarcoma-associated herpesvirus1. It broadly infects humans and other vertebrate animals and causes var

Developmental convergence and divergence in human stem cell models of autism

Abstract Two decades of genetic studies in autism spectrum disorder (ASD) have identified more than 100 genes harbouring rare risk mutations1,2,3,4,5,6,7,8,9,10,11,12,13. Despite this substantial heterogeneity, transcriptomic and epigenetic analyses have identified convergent patterns of dysregulat

Accurate determination of the 3D atomic structure of amorphous materials